J Child Neurol. Tuberous sclerosis, otherwise referred to as Bourneville's disease or tuberous sclerosis complex, is an inherited disease that affects multiple systems. 16 Department of Neurology and Epileptology, The Children's Memorial Health Institute, Warsaw, Poland. Observations: Tuberous sclerosis is a systemic disorder (incidence one in 10 000) characterized by benign growths (hamartias and hamartomas) in multiple organ systems. Tuberous sclerosis complex (TSC) is a genetic disorder affecting cellular differentiation, proliferation, and migration early in development, resulting in a variety of hamartomatous lesions that may affect virtually every organ system of the body. It varies in the severity with which it affects people – some people are severely affected and diagnosed early, others are only found to have the condition when their child is diagnosed. METHODS 179 patients identified were in a prevalence study of TSC in the south of England and 107 of these agreed to full ophthalmic … skin, eyes, and nervous system). 15 Department of Child Neurology, Medical University of Warsaw, Warsaw, Poland. TSC can also result in the death of the individual. 13 European Tuberous Sclerosis Complex Association, Dattein, Germany. BACKGROUND/AIMS Tuberous sclerosis complex (TSC) has retinal and non-retinal ophthalmic manifestations. TS Alliance is dedicated to finding a cure for tuberous sclerosis complex (TSC) … National Tuberous Sclerosis Association. Pediatr Neurol, 49 , 255-265 There is also a BMJ learning module on the diagnosis and management of Tuberous Sclerosis , funded by, and developed in association with, the Tuberous Sclerosis Association Tuberous sclerosis–associated neuropsychiatric disorders symptoms overlap with clinical criteria for frontotemporal dementia, yet the association between the 2 has not been explored. The Tuberous Sclerosis Association (TSA), an international, self-help organization located in the United Kingdom, was established in 1977 by a group of parents and interested physicians dedicated to providing support to individuals with tuberous sclerosis (TS) and their families, increasing awareness of the disorder, and promoting fundraising to support research. National Tuberous Sclerosis Association, Inc. (TS Alliance), d/b/a Tuberous Sclerosis Alliance, is a not-for-profit organization incorporated in the State of California on March 15, 1975. DEA Disseminating Expertise and Achievement across the EU Aim To create a readily accessible, active and sustainable network within and between EU countries, for people affected by Tuberous Sclerosis Complex. It is The Tuberous Sclerosis Association. Tuberous Sclerosis Association: "An Introduction to Tuberous Sclerosis Complex." Tuberous Sclerosis Complex (TSC) is a genetic disease caused by mutations in the tumour suppressor genes TSC1 and TSC2, located on chromosomes 9 and 16. In a quarter of a century, significant progress in tuberous sclerosis complex has been made. Tuberous sclerosis complex (TSC) is associated with a wide range of cognitive, behavioral and psychiatric manifestations. Tuberous Sclerosis Complex (TSC) is a genetic disorder that causes tumours to grow in all parts of the body. TTSA - The Tuberous Sclerosis Association. TS affects approximately 1 in 6000 people, and almost 1 million people live with this disease worldwide. Tuberous sclerosis (TS) is a rare genetic disorder in which benign (noncancerous) tumors grow throughout the body. What is Tuberous Sclerosis? The Tuberous Sclerosis Association listed as TTSA. 1998 Dec. 13(12):624-8. . It usually affects the central nervous system. 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